Plasmid
Part:BBa_K2908681:Design
Designed by: Dong Yufan Group: iGEM19_CSU_CHINA (2019-10-17)
s(ESR1)p-miR101spe-EGFP
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 155
- 21INCOMPATIBLE WITH RFC[21]Illegal XhoI site found at 200
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The initiation codon ATG can only appear between miRNA sponse and EGFP.
The construction method is the same as module1, only except the paired sequence of each inserted fragment, which shows in the following picture.
Source
We designed it by ourselves and constructed this part with the help of Golden gate.
References
Waclaw Szybalski”, Sun C. Kim”, Noaman Hasan” and Anna J. Podhajskab, Class IIS restriction enzymes, a review.1991, Gene, 100: 13-26.